Assay Detail
Functional
CHEMBL5128490
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human SK-N-SH cells harboring wildtype TP53 assessed as reduction in cell viability and measured upto 72 hrs by XTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-N-SH |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small-molecule MDM2 inhibitors in clinical trials for cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.66 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5198325 | — | — | 1 | 7.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5198325 | — | IC50 | = | 21.9 | nM | 7.66 |