Assay Detail
Functional
CHEMBL5128600
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 infected in human erythrocytes incubated for 72 hrs by parasite lactate dehydrogenase assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Cell Type | Erythrocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Spiral molecules with antimalarial activities: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.10 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL517778 | ERYSOVINE | — | 1 | 5.39 |
| CHEMBL446533 | ERYSODINE | — | 1 | 5.19 |
| CHEMBL518262 | ERYTHRALINE | — | 1 | 5.14 |
| CHEMBL442947 | ERYSOTRINE | — | 1 | 4.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL517778 | ERYSOVINE | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL446533 | ERYSODINE | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL518262 | ERYTHRALINE | IC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL442947 | ERYSOTRINE | IC50 | = | 20600.0 | nM | 4.69 |