Compound Detail
CHEMBL518262
ERYTHRALINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL518262 |
| Name | ERYTHRALINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TVOFUERNMZTYRM-KSSFIOAISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
297.4
MW (Da)
2.38
ALogP
4
HBA
0
HBD
30.9
PSA (Ų)
0.80
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 5.14 | 5.14 | 7300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 7300.0 | nM | 5.14 | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 inf... | 35461019 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19026536 | 10.1016/j.bmcl.2008.10.111 | Jurkat | 2 |
| 35461019 | 10.1016/j.ejmech.2022.114361 | Plasmodium falciparum | 1 |
| 35461019 | 10.1016/j.ejmech.2022.114361 | MRC5 | 1 |
Data from ChEMBL 36 via Core Engine