Assay Detail
Functional
CHEMBL5130299
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Antiproliferative activity against human LNCaP cells assessed as reduction in cell viability by CellTitre-Glo assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Application of Degradation of Cyclic-AMP Response Element Binding Protein for the Potential Treatment of Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 9.14 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5203778 | — | — | 1 | 10.00 |
| CHEMBL5205159 | — | — | 1 | 10.00 |
| CHEMBL5183992 | — | — | 1 | 10.00 |
| CHEMBL5173006 | — | — | 1 | 9.52 |
| CHEMBL5191359 | — | — | 1 | 9.52 |
| CHEMBL5180617 | — | — | 1 | 9.40 |
| CHEMBL5192095 | — | — | 1 | 9.15 |
| CHEMBL5194773 | — | — | 1 | 9.10 |
| CHEMBL5205413 | — | — | 1 | 9.10 |
| CHEMBL5209070 | — | — | 1 | 9.05 |
| CHEMBL5179729 | — | — | 1 | 7.48 |
| CHEMBL5187614 | — | — | 1 | 7.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5203778 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL5205159 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL5183992 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL5173006 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL5191359 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL5180617 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL5192095 | — | IC50 | = | 0.7 | nM | 9.15 |
| CHEMBL5194773 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL5205413 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL5209070 | — | IC50 | = | 0.9 | nM | 9.05 |
| CHEMBL5179729 | — | IC50 | = | 33.1 | nM | 7.48 |
| CHEMBL5187614 | — | IC50 | = | 44.5 | nM | 7.35 |