Assay Detail
Binding
CHEMBL5131610
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Inhibition of GAK (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.57 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1287853 | FEDRATINIB | 4.0 | 1 | 9.00 |
| CHEMBL4642467 | — | — | 1 | 7.62 |
| CHEMBL553 | ERLOTINIB | 4.0 | 1 | 7.42 |
| CHEMBL1789941 | RUXOLITINIB | 4.0 | 1 | 6.92 |
| CHEMBL2105759 | BARICITINIB | 4.0 | 1 | 6.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1287853 | FEDRATINIB | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4642467 | — | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL553 | ERLOTINIB | IC50 | = | 38.0 | nM | 7.42 |
| CHEMBL1789941 | RUXOLITINIB | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL2105759 | BARICITINIB | IC50 | = | 136.0 | nM | 6.87 |