Assay Detail
Binding
CHEMBL5131633
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of AXL (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein kinase receptor UFO (CHEMBL4895) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.50 | 9.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3301622 | GILTERITINIB | 4.0 | 1 | 9.14 |
| CHEMBL3809489 | BEMCENTINIB | 2.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3301622 | GILTERITINIB | IC50 | = | 0.73 | nM | 9.14 |
| CHEMBL3809489 | BEMCENTINIB | IC50 | = | 14.0 | nM | 7.85 |