Assay Detail
Functional
CHEMBL5131699
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Antiviral activity against ZIKV
9
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Zika virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.84 | 7.62 |
| EC50 | 4 | 5.71 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL14762 | SELICICLIB | 2.0 | 1 | 7.62 |
| CHEMBL5209307 | — | — | 1 | 7.05 |
| CHEMBL5193007 | — | — | 1 | 7.05 |
| CHEMBL535 | SUNITINIB | 4.0 | 1 | 6.29 |
| CHEMBL4556306 | — | — | 1 | 5.72 |
| CHEMBL583194 | — | — | 2 | 5.64 |
| CHEMBL553 | ERLOTINIB | 4.0 | 1 | 5.20 |
| CHEMBL1650595 | AR-12 | 1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL14762 | SELICICLIB | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL5209307 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL5193007 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL535 | SUNITINIB | EC50 | = | 510.0 | nM | 6.29 |
| CHEMBL4556306 | — | EC50 | = | 1910.0 | nM | 5.72 |
| CHEMBL583194 | — | EC50 | = | 2280.0 | nM | 5.64 |
| CHEMBL583194 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL553 | ERLOTINIB | EC50 | = | 6280.0 | nM | 5.20 |
| CHEMBL1650595 | AR-12 | IC50 | < | 2000.0 | nM | - |