Assay Detail
Binding
CHEMBL5131758
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Inhibition of c-Abl (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.43 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL288441 | BOSUTINIB | 4.0 | 1 | 9.00 |
| CHEMBL1642 | IMATINIB MESYLATE | 4.0 | 1 | 6.72 |
| CHEMBL5416410 | DASATINIB | 4.0 | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL288441 | BOSUTINIB | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL1642 | IMATINIB MESYLATE | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL5416410 | DASATINIB | IC50 | = | 270.0 | nM | 6.57 |