Assay Detail

CHEMBL5131774

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Functional

Antiviral activity against JUNV

ChEMBL ↗

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Target

Junin virus (CHEMBL4523072) ↗

Open DB target context

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Junin virus (CHEMBL4523072) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Junin virus

CHEMBL4523072

Anchored from Assay target.

Protein identity Junin virus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mammarenavirus juninense
Confidence	1 — Organism
Curated By	Autocuration

Target

Junin virus (CHEMBL4523072) ↗

Type	ORGANISM
Organism	Mammarenavirus juninense

Publication

Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.

Raghuvanshi R, Bharate SB.
J Med Chem (2022) 65 : 893 -921
PubMed 33539089 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	5.29	5.77

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL553	ERLOTINIB	4.0	1	5.77
CHEMBL999	—	—	1	4.80

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL553	ERLOTINIB	EC50	=	1700.0	nM	5.77
CHEMBL999	—	EC50	=	16000.0	nM	4.80