Assay Detail

CHEMBL5131811

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Functional

Antiviral activity against GFP-tagged EBOV

ChEMBL ↗

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Target

Ebolavirus (CHEMBL4434621) ↗

Open DB target context

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Primary target Ebolavirus

CHEMBL4434621

Anchored from Assay target.

Protein identity Ebolavirus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Ebolavirus
Confidence	1 — Organism
Curated By	Autocuration

Target

Ebolavirus (CHEMBL4434621) ↗

Type	ORGANISM
Organism	Ebolavirus

Publication

Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.

Raghuvanshi R, Bharate SB.
J Med Chem (2022) 65 : 893 -921
PubMed 33539089 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	6.24	6.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1650595	AR-12	1.0	1	6.52
CHEMBL258940	FALNIDAMOL	2.0	1	5.96

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1650595	AR-12	EC50	=	300.0	nM	6.52
CHEMBL258940	FALNIDAMOL	EC50	=	1100.0	nM	5.96