Assay Detail
Binding
CHEMBL5131965
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Inhibition of EGFR (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Kinase Inhibitors as Underexplored Antiviral Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.73 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL553 | ERLOTINIB | 4.0 | 1 | 8.70 |
| CHEMBL7917 | TYRPHOSTIN AG-1478 | — | 1 | 8.52 |
| CHEMBL939 | GEFITINIB | 4.0 | 1 | 7.48 |
| CHEMBL44 | GENISTEIN | 2.0 | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL553 | ERLOTINIB | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL7917 | TYRPHOSTIN AG-1478 | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL939 | GEFITINIB | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL44 | GENISTEIN | IC50 | = | 600.0 | nM | 6.22 |