Assay Detail
Binding
CHEMBL5133652
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Mixed type inhibition of AChE (unknown origin) assessed as inhibitory constant by Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Acetylcholine receptor subunit epsilon (CHEMBL2484) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of novel 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives as balanced multifunctional agents against Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.92 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5176418 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5176418 | — | Ki | = | 120.0 | nM | 6.92 |