Assay Detail
Functional
CHEMBL5135181
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Antiinflammatory activity against human HaCaT cells assessed as inhibition of UVB irradiation-induced PGE2 production measured after 2 hrs by ELISA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HaCaT |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Adiponectin-Secretion-Promoting Cyclic Peptide-Polyketide Hybrids from a Halophyte-Associated Fungus, <i>Colletotrichum gloeosporioides</i> JS0417.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.86 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL226545 | TRYPTOPHOL | — | 1 | 5.18 |
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 4.74 |
| CHEMBL25 | ASPIRIN | 4.0 | 1 | 4.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL226545 | TRYPTOPHOL | IC50 | = | 6550.0 | nM | 5.18 |
| CHEMBL165 | RESVERATROL | IC50 | = | 18310.0 | nM | 4.74 |
| CHEMBL25 | ASPIRIN | IC50 | = | 21270.0 | nM | 4.67 |