Assay Detail
Binding
CHEMBL5135395
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat intestinal isomaltase assessed as release of p-nitrophenol using p-nitrophenyl glycoside as substrate by spectrometric assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and glycosidase inhibition of C-4 branched LAB and DAB derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.38 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL406973 | — | — | 1 | 6.44 |
| CHEMBL2177689 | — | — | 1 | 5.70 |
| CHEMBL5198563 | — | — | 1 | 4.89 |
| CHEMBL5189075 | — | — | 1 | 4.50 |
| CHEMBL5192700 | — | — | 1 | - |
| CHEMBL5202712 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL406973 | — | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL2177689 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL5198563 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL5189075 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL5192700 | — | IC50 | = | 113000.0 | nM | - |
| CHEMBL5202712 | — | IC50 | = | 650000.0 | nM | - |