Assay Detail
Binding
CHEMBL5135627
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PARP16 (unknown origin) using 6xHis-tagged IRE-1 as substrate incubated for 1 hr by chemiluminescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein mono-ADP-ribosyltransferase PARP16 (CHEMBL4105981) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.44 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5189477 | — | — | 1 | 6.44 |
| CHEMBL5178746 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5189477 | — | IC50 | = | 362.0 | nM | 6.44 |
| CHEMBL5178746 | — | IC50 | = | 296300.0 | nM | - |