Assay Detail
Binding
CHEMBL5137799
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant PKM2 (unknown origin) Ile335, Lys367, Lys207, Thr129, Lys206, Lys207, Asn75, Hie78 residues
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.67 | 5.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL276915 | 7-HYDROXYFLAVONE | — | 1 | 5.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL276915 | 7-HYDROXYFLAVONE | IC50 | = | 2120.0 | nM | 5.67 |