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Assay Detail

CHEMBL5138017

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Toxicity
Antiproliferative activity against mouse Swiss-3T3 cells assessed as cell growth inhibition incubated for 72 hrs by cell counter method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Mus musculus
Cell Type NIH3T3
Confidence 1 — Organism
Curated By Autocuration

Target

NIH3T3 (CHEMBL614822)
Type CELL-LINE
Organism Mus musculus

Publication

How the structural properties of the indole derivatives are important in kinase targeted drug design?: A case study on tyrosine kinase inhibitors.
Mondal D, Amin SA, Moinul M, Das K, Jha T, Gayen S.
Bioorg Med Chem (2022) 53 : 116534 -116534
PubMed 34864496 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.72 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5205062 1 5.72
CHEMBL294205 1 5.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5205062 IC50 = 1900.0 nM 5.72
CHEMBL294205 IC50 = 1900.0 nM 5.72