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Assay Detail

CHEMBL5138498

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Binding
Inhibition of Helicobacter pylori urease assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Helicobacter pylori
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Urease subunit alpha/Urease subunit beta (CHEMBL3885651)
Type PROTEIN COMPLEX
Organism Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)

Publication

An overview on the synthetic urease inhibitors with structure-activity relationship and molecular docking.
Yang W, Feng Q, Peng Z, Wang G.
Eur J Med Chem (2022) 234 : 114273 -114273
PubMed 35305460 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.85 7.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2425469 1 7.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2425469 Ki = 14.0 nM 7.85