Urease subunit alpha/Urease subunit beta · PROTEIN COMPLEX · Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)
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As of 2026-09-14Protein identity stays anchored to UniProt P69996. Use UniProt P69996 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P69996 as the stable identity anchor, then attach disease evidence before program review.
Urease subunit beta
Review this target as Urease subunit alpha/Urease subunit beta, mapped to UniProt P69996. ChEMBL maps the protein component as Urease subunit beta. Sequence length is 569 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Urease subunit alpha/Urease subunit beta as ChEMBL target CHEMBL3885651, mapped to UniProt P69996. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Urease subunit alpha/Urease subunit beta is the right protein anchor across sources, using UniProt P69996 as the stable mapping.
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| Preferred Name | Urease subunit alpha/Urease subunit beta |
| Target Type | PROTEIN COMPLEX |
| Organism | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) |
| UniProt | P69996 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Urease subunit beta |
| UniProt Accession | P69996 |
| Component Type | Protein |
| Sequence Length | 569 aa |
Urease subunit beta
Review this target as Urease subunit alpha/Urease subunit beta, mapped to UniProt P69996. ChEMBL maps the protein component as Urease subunit beta. Sequence length is 569 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5209436 | 9.47 | Kd | 0.34 | Preclinical |
| CHEMBL2425469 | 7.85 | Ki | 14.0 | Preclinical |
| CHEMBL4172924 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL4167553 | 7.37 | IC50 | 43.0 | Preclinical |
| CHEMBL4251246 | 7.37 | Ki | 43.0 | Preclinical |
| CHEMBL2425478 | 7.35 | Ki | 45.0 | Preclinical |
| CHEMBL4162915 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL4243350 | 7.21 | IC50 | 61.0 | Preclinical |
| CHEMBL5209436 | 7.19 | Ki | 65.0 | Preclinical |
| CHEMBL2425469 | 7.08 | IC50 | 83.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 37 | 180 | 5.2 |
| assay format | 30 | 142 | 4.8 |