Assay Detail
Binding
CHEMBL5138526
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tubulin polymerization (unknown origin) measured every 3 secs for 1 hr by spectroflourimetric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.01 | 10.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5194719 | — | — | 1 | 10.26 |
| CHEMBL5203711 | — | — | 1 | 9.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5194719 | — | IC50 | = | 0.0551 | nM | 10.26 |
| CHEMBL5203711 | — | IC50 | = | 0.176 | nM | 9.75 |