Assay Detail
Binding
CHEMBL5138527
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EGFR (unknown origin) by microplate reader
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.21 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1782692 | — | — | 1 | 7.51 |
| CHEMBL5206193 | — | — | 1 | 7.07 |
| CHEMBL5190121 | — | — | 1 | 7.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1782692 | — | IC50 | = | 31.2 | nM | 7.51 |
| CHEMBL5206193 | — | IC50 | = | 85.4 | nM | 7.07 |
| CHEMBL5190121 | — | IC50 | = | 86.7 | nM | 7.06 |