Assay Detail
Binding
CHEMBL5138529
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tubulin polymerization (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.51 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5206193 | — | — | 1 | 7.06 |
| CHEMBL1782692 | — | — | 1 | 6.96 |
| CHEMBL4116552 | — | — | 1 | 6.32 |
| CHEMBL4569885 | — | — | 1 | 6.15 |
| CHEMBL4117373 | — | — | 1 | 6.04 |
| CHEMBL4099329 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5206193 | — | IC50 | = | 87.6 | nM | 7.06 |
| CHEMBL1782692 | — | IC50 | = | 108.4 | nM | 6.96 |
| CHEMBL4116552 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL4569885 | — | IC50 | = | 710.0 | nM | 6.15 |
| CHEMBL4117373 | — | IC50 | = | 910.0 | nM | 6.04 |
| CHEMBL4099329 | — | IC50 | > | 20000.0 | nM | - |