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Assay Detail

CHEMBL5139924

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against MERS-CoV assessed as viral growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Middle East respiratory syndrome-related coronavirus
Confidence 1 — Organism
Curated By Autocuration

Target

Middle East respiratory syndrome-related coronavirus (CHEMBL4296578)
Type ORGANISM
Organism Middle East respiratory syndrome-related coronavirus

Publication

Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.
Tan H, Hu Y, Jadhav P, Tan B, Wang J.
J Med Chem (2022) 65 : 7561 -7580
PubMed 35620927 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.68 7.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL55400 PROFLAVINE 2.0 1 7.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL55400 PROFLAVINE IC50 = 21.0 nM 7.68