Assay Detail
Functional
CHEMBL5140840
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Potentiation of vancomycin-induced antibacterial activity against methicillin resistant Staphylococcus aureus Mu50 in presence of vancomycin
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Staphylococcus aureus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small Carbohydrate Derivatives as Potent Antibiofilm Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.32 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4078565 | — | — | 1 | 5.90 |
| CHEMBL4072752 | — | — | 1 | 5.43 |
| CHEMBL4077423 | — | — | 1 | 5.10 |
| CHEMBL3590184 | — | — | 1 | 5.10 |
| CHEMBL5205021 | — | — | 1 | 5.08 |
| CHEMBL491592 | HAMAMELITANNIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4078565 | — | EC50 | = | 1270.0 | nM | 5.90 |
| CHEMBL4072752 | — | EC50 | = | 3710.0 | nM | 5.43 |
| CHEMBL4077423 | — | EC50 | = | 7980.0 | nM | 5.10 |
| CHEMBL3590184 | — | EC50 | = | 7970.0 | nM | 5.10 |
| CHEMBL5205021 | — | EC50 | = | 8290.0 | nM | 5.08 |
| CHEMBL491592 | HAMAMELITANNIN | EC50 | = | 165000.0 | nM | - |