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Assay Detail

CHEMBL5140880

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Pseudomonas aeruginosa LecB assessed as dissociation constant by isothermal titration calorimetry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas aeruginosa
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Fucose-binding lectin PA-IIL (CHEMBL4523938)
Type SINGLE PROTEIN
Organism Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)

Publication

Small Carbohydrate Derivatives as Potent Antibiofilm Agents.
Singh K, Kulkarni SS.
J Med Chem (2022) 65 : 8525 -8549
PubMed 35777073 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 4.80 4.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3800313 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3800313 Kd = 16000.0 nM 4.80