Assay Detail
Binding
CHEMBL5140898
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human Androgen receptor
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 8.98 | 9.70 |
| Kd | 1 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL436784 | — | — | 1 | 9.70 |
| CHEMBL484726 | — | — | 1 | 9.70 |
| CHEMBL717 | MEDROXYPROGESTERONE ACETATE | 4.0 | 1 | 9.00 |
| CHEMBL5187916 | — | — | 1 | 8.96 |
| CHEMBL227088 | — | — | 1 | 8.96 |
| CHEMBL390728 | — | — | 1 | 8.40 |
| CHEMBL467888 | LGD-2941 | 1.0 | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL436784 | — | EC50 | = | 0.2 | nM | 9.70 |
| CHEMBL484726 | — | EC50 | = | 0.2 | nM | 9.70 |
| CHEMBL717 | MEDROXYPROGESTERONE ACETATE | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL5187916 | — | EC50 | = | 1.1 | nM | 8.96 |
| CHEMBL227088 | — | EC50 | = | 1.1 | nM | 8.96 |
| CHEMBL390728 | — | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL467888 | LGD-2941 | EC50 | = | 7.1 | nM | 8.15 |