Assay Detail
Binding
CHEMBL5140937
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at Androgen receptor in human LNCaP cells measured by SEAP reporter gene assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.11 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5189989 | — | — | 1 | 6.90 |
| CHEMBL3932464 | — | — | 1 | 6.82 |
| CHEMBL362566 | — | — | 1 | 5.41 |
| CHEMBL5186356 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5189989 | — | IC50 | = | 125.0 | nM | 6.90 |
| CHEMBL3932464 | — | IC50 | = | 153.0 | nM | 6.82 |
| CHEMBL362566 | — | IC50 | = | 3920.0 | nM | 5.41 |
| CHEMBL5186356 | — | IC50 | = | 4750.0 | nM | 5.32 |