Assay Detail
Binding
CHEMBL5140945
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Binding affinity to wild-type Androgen receptor (unknown origin)
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.84 | 7.47 |
| Ki | 1 | 6.96 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1957608 | — | — | 1 | 7.47 |
| CHEMBL5201606 | — | — | 1 | 7.43 |
| CHEMBL518945 | — | — | 1 | 6.96 |
| CHEMBL5192915 | — | — | 1 | 6.37 |
| CHEMBL2337513 | — | — | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1957608 | — | IC50 | = | 34.0 | nM | 7.47 |
| CHEMBL5201606 | — | IC50 | = | 37.0 | nM | 7.43 |
| CHEMBL518945 | — | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL5192915 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL2337513 | — | IC50 | = | 830.0 | nM | 6.08 |