Assay Detail
Binding
CHEMBL5140946
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to bicalutamide-resistant Androgen receptor T877A mutant (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.76 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5201606 | — | — | 1 | 7.00 |
| CHEMBL1957608 | — | — | 1 | 6.80 |
| CHEMBL5192915 | — | — | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5201606 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1957608 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL5192915 | — | IC50 | = | 340.0 | nM | 6.47 |