Assay Detail
Binding
CHEMBL5140948
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Antagonist activity at Androgen receptor T877A mutant (unknown origin) expressed in African green monkey COS-7 cells measured as gene transcription level
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS-7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.55 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5201606 | — | — | 1 | 6.96 |
| CHEMBL5192915 | — | — | 1 | 6.72 |
| CHEMBL1957608 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5201606 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL5192915 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL1957608 | — | IC50 | = | 1100.0 | nM | 5.96 |