Assay Detail
Binding
CHEMBL5140957
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to bicalutamide-resistant Androgen receptor T878A mutant (unknown origin)
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.77 | 5.77 |
| Ki | 1 | 8.22 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL518945 | — | — | 1 | 8.22 |
| CHEMBL2337513 | — | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL518945 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL2337513 | — | IC50 | = | 1700.0 | nM | 5.77 |