Assay Detail

CHEMBL5140983

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Functional

Antiproliferative activity against NTD-over expressed human HEK293T cells after 5 days by MTS assay

ChEMBL ↗

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Target

HEK-293T (CHEMBL3706568) ↗

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HEK-293T (CHEMBL3706568) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target HEK-293T

CHEMBL3706568

Anchored from Assay target.

Protein identity HEK-293T

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HEK-293T
Confidence	1 — Organism
Curated By	Autocuration

Target

HEK-293T (CHEMBL3706568) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Therapeutic Strategies to Target the Androgen Receptor.

Xiang W, Wang S.
J Med Chem (2022) 65 : 8772 -8797
PubMed 35786895 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.11	6.11

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5205059	—	—	1	6.11

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5205059	—	IC50	=	780.0	nM	6.11