Assay Detail
Binding
CHEMBL5142618
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Binding affinity to human BChE assessed as dissociation constant by surface plasmon resonance assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
<i>N</i>-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 9.81 | 10.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5201089 | — | — | 1 | 10.19 |
| CHEMBL5195228 | — | — | 1 | 9.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5201089 | — | Kd | = | 0.064 | nM | 10.19 |
| CHEMBL5195228 | — | Kd | = | 0.37 | nM | 9.43 |