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Assay Detail

CHEMBL5143243

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A-431 cells assessed as inhibition of cell growth incubated for 5 days by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A-431
Confidence 1 — Organism
Curated By Autocuration

Target

A-431 (CHEMBL614069)
Type CELL-LINE
Organism Homo sapiens

Publication

Alliacane-Type Secondary Metabolites from Submerged Cultures of the Basidiomycete <i>Clitocybe nebularis</i>.
Schrey H, Scheele T, Ulonska C, Nedder DL, Neudecker T, Spiteller P, Stadler M.
J Nat Prod (2022) 85 : 2363 -2371
PubMed 36130285 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.84 8.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5175478 1 8.51
CHEMBL5174158 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5175478 IC50 = 3.1 nM 8.51
CHEMBL5174158 IC50 = 7000.0 nM 5.16