Assay Detail
Binding
CHEMBL5146014
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of JNK1 in mouse JB6 C1 41 cell lysate incubated for 1 hr relative to control
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | JB6 Cl 41-5a |
| Subcellular | Lysate |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Mitogen-activated protein kinase 8 (CHEMBL1795174) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Unraveling the Design and Discovery of c-Jun N-Terminal Kinase Inhibitors and Their Therapeutic Potential in Human Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.34 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL413552 | QUERCETAGETIN | — | 1 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL413552 | QUERCETAGETIN | IC50 | = | 4600.0 | nM | 5.34 |