Assay Detail
Toxicity
CHEMBL5146630
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Cytotoxicity against human HaCaT cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Blue cell viability assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | HaCaT |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimicrobial Prenylated Isoflavones from the Leaves of the Amazonian Medicinal Plant <i>Vatairea guianensis</i> Aubl.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.16 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 4.30 |
| CHEMBL5174986 | — | — | 1 | 4.16 |
| CHEMBL5170827 | — | — | 1 | 4.09 |
| CHEMBL5177554 | — | — | 1 | 4.07 |
| CHEMBL3616491 | — | — | 1 | - |
| CHEMBL5172980 | — | — | 1 | - |
| CHEMBL5180194 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL5174986 | — | IC50 | = | 69800.0 | nM | 4.16 |
| CHEMBL5170827 | — | IC50 | = | 80700.0 | nM | 4.09 |
| CHEMBL5177554 | — | IC50 | = | 85900.0 | nM | 4.07 |
| CHEMBL3616491 | — | IC50 | = | 159800.0 | nM | - |
| CHEMBL5172980 | — | IC50 | = | 134600.0 | nM | - |
| CHEMBL5180194 | — | IC50 | = | 207000.0 | nM | - |