Assay Detail
Functional
CHEMBL5147983
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Antiviral activity against HIV-1 JRFL assessed as inhibition of viral growth
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 9.84 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL236995 | — | — | 1 | 10.30 |
| CHEMBL2332337 | — | — | 1 | 10.15 |
| CHEMBL238103 | — | — | 1 | 9.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL236995 | — | EC50 | = | 0.05 | nM | 10.30 |
| CHEMBL2332337 | — | EC50 | = | 0.07 | nM | 10.15 |
| CHEMBL238103 | — | EC50 | = | 0.88 | nM | 9.06 |