Assay Detail
Binding
CHEMBL5148094
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant MAGL (unknown origin) expressed in COS7 cells assessed as blockade of substrate hydrolysis using AEA as substrate preincubated with compound for 30 mins followed by susbstrate addition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL606201 | — | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL606201 | — | IC50 | = | 4.0 | nM | 8.40 |