Assay Detail
Binding
CHEMBL5148588
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Binding affinity to PAR4 (unknown origin) assessed as saturation binding
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 10.01 | 10.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3716726 | — | — | 1 | 10.01 |
| CHEMBL3716552 | BMS-986141 | 2.0 | 1 | 10.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3716726 | — | Kd | = | 0.098 | nM | 10.01 |
| CHEMBL3716552 | BMS-986141 | Kd | = | 0.1 | nM | 10.00 |