Assay Detail
Binding
CHEMBL5150826
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to FLT3-ITD-F691L mutant (unknown origin) assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Aurora kinase B/Receptor-type tyrosine-protein kinase (CHEMBL3430908) ↗| Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
Publication
FLT3 Inhibitors in Acute Myeloid Leukemia: Challenges and Recent Developments in Overcoming Resistance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 10.92 | 10.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5176837 | — | — | 1 | 10.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5176837 | — | Kd | = | 0.012 | nM | 10.92 |