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Assay Detail

CHEMBL5150849

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DDR1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Epithelial discoidin domain-containing receptor 1 (CHEMBL5319)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

FLT3 Inhibitors in Acute Myeloid Leukemia: Challenges and Recent Developments in Overcoming Resistance.
Wang Z, Cai J, Cheng J, Yang W, Zhu Y, Li H, Lu T, Chen Y, Lu S.
J Med Chem (2021) 64 : 2878 -2900
PubMed 33719439 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.07 8.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5176837 1 8.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5176837 IC50 = 8.5 nM 8.07