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Assay Detail

CHEMBL5151786

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Zika virus SMGC-1 infected in human Huh-7 cells assessed as reduction in viral titer
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Zika virus
Cell Type Huh-7
Confidence 1 — Organism
Curated By Autocuration

Target

Zika virus (CHEMBL4296612)
Type ORGANISM
Organism Zika virus

Publication

Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
Nascimento IJDS, Santos-Júnior PFDS, Aquino TM, Araújo-Júnior JX, Silva-Júnior EFD.
Eur J Med Chem (2021) 224 : 113698 -113698
PubMed 34274831 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.13 5.13

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5180295 1 5.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5180295 EC50 = 7430.0 nM 5.13