Assay Detail
Binding
CHEMBL5152116
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Binding affinity to Bacillus anthracis lethal factor assessed as inhibition constant
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus anthracis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Zinc enzymes in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.38 | 9.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5180162 | — | — | 1 | 9.57 |
| CHEMBL5203076 | — | — | 1 | 8.19 |
| CHEMBL184618 | FRAMYCETIN | 3.0 | 1 | 8.15 |
| CHEMBL204593 | — | — | 1 | 7.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5180162 | — | Ki | = | 0.27 | nM | 9.57 |
| CHEMBL5203076 | — | Ki | = | 6.4 | nM | 8.19 |
| CHEMBL184618 | FRAMYCETIN | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL204593 | — | Ki | = | 24.0 | nM | 7.62 |