Assay Detail
Binding
CHEMBL5152336
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Binding affinity to RAGE (unknown origin) assessed as dissociation constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Advanced glycosylation end product-specific receptor (CHEMBL2176846) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.41 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5176926 | — | — | 1 | 9.00 |
| CHEMBL5200484 | — | — | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5176926 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL5200484 | — | Kd | = | 15.0 | nM | 7.82 |