Assay Detail
Binding
CHEMBL5152497
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human GSTA1-1 using GSH and CDNB as substrate preincubated for 2 mins followed by substrate addition and measured upto 6 mins in the presence of UV irradiation by spectrophotometric analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of glutathione S-transferases by photoactive calix[4]arene α-ketophosphonic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.37 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5169380 | — | — | 1 | 6.89 |
| CHEMBL5178537 | — | — | 1 | 6.89 |
| CHEMBL5174343 | — | — | 1 | 6.47 |
| CHEMBL5199600 | — | — | 1 | 6.37 |
| CHEMBL5184218 | — | — | 1 | 5.86 |
| CHEMBL5203780 | — | — | 1 | 5.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5169380 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL5178537 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL5174343 | — | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL5199600 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL5184218 | — | IC50 | = | 1370.0 | nM | 5.86 |
| CHEMBL5203780 | — | IC50 | = | 1870.0 | nM | 5.73 |