Assay Detail
Binding
CHEMBL5152646
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine kidney DAAO using D-serine as substrate assessed as H2O2 formation by amplex red and peroxidase-coupled continuous fluorescence spectrophotometric analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The inhibition of monoamine oxidase by 2H-1,4-benzothiazin-3(4H)-ones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.17 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL391574 | — | — | 1 | 6.03 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 5.97 |
| CHEMBL5180307 | — | — | 1 | 5.38 |
| CHEMBL5174014 | — | — | 1 | 4.32 |
| CHEMBL5199383 | — | — | 1 | 4.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL391574 | — | IC50 | = | 933.0 | nM | 6.03 |
| CHEMBL140 | CURCUMIN | IC50 | = | 1070.0 | nM | 5.97 |
| CHEMBL5180307 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL5174014 | — | IC50 | = | 47500.0 | nM | 4.32 |
| CHEMBL5199383 | — | IC50 | = | 73200.0 | nM | 4.13 |