Assay Detail
Binding
CHEMBL5152857
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Mixed type inhibition of Helicobacter pyroli urease assessed as dissociation constant for ESI complex by microplate reader analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Helicobacter pylori |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Urease subunit alpha/Urease subunit beta (CHEMBL3885651) ↗| Type | PROTEIN COMPLEX |
| Organism | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) |
Publication
Synthesis, evaluation and mechanism exploration of 2-(N-(3-nitrophenyl)-N-phenylsulfonyl)aminoacetohydroxamic acids as novel urease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.92 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5209436 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5209436 | — | Ki | = | 1200.0 | nM | 5.92 |