Assay Detail
ADMET
CHEMBL5155964
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Inhibition of CYP1A2 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A<sub>3</sub> adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.17 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5202349 | — | — | 1 | 6.60 |
| CHEMBL5180330 | — | — | 1 | 6.37 |
| CHEMBL4571380 | — | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5202349 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5180330 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL4571380 | — | IC50 | = | 2890.0 | nM | 5.54 |