Assay Detail
Functional
CHEMBL5161533
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Anticoagulant activity in human platelet poor plasma assessed as inhibition of thrombin generation incubated for 3 mins by calibrated automated thrombogram analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Chemical synthesis and pharmacological properties of heparin pentasaccharide analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.88 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5180987 | — | — | 1 | 4.92 |
| CHEMBL5203721 | — | — | 1 | 4.91 |
| CHEMBL5176075 | — | — | 1 | 4.90 |
| CHEMBL1200644 | FONDAPARINUX SODIUM | 4.0 | 1 | 4.84 |
| CHEMBL5207683 | — | — | 1 | 4.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5180987 | — | IC50 | = | 12170.0 | nM | 4.92 |
| CHEMBL5203721 | — | IC50 | = | 12390.0 | nM | 4.91 |
| CHEMBL5176075 | — | IC50 | = | 12530.0 | nM | 4.90 |
| CHEMBL1200644 | FONDAPARINUX SODIUM | IC50 | = | 14510.0 | nM | 4.84 |
| CHEMBL5207683 | — | IC50 | = | 14820.0 | nM | 4.83 |