Assay Detail
Binding
CHEMBL5164486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | Hepa1c1c7 |
| Subcellular | Cytosol |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.05 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1324296 | — | — | 1 | 8.00 |
| CHEMBL5198290 | — | — | 1 | 7.06 |
| CHEMBL5179114 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1324296 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL5198290 | — | Ki | = | 88.0 | nM | 7.06 |
| CHEMBL5179114 | — | Ki | = | 800.0 | nM | 6.10 |